The workhorse approach for pesticide residue analysis involves using gas chromatography and liquid chromatography tandem mass spectrometry (MS/MS) in the ion transition mode.
For potency analysis via HPLC, grinding/homogenization and alcohol extraction is a common sample prep technique for dried flower and extracts.
The introduction of a series of articles focusing on the applications of instruments for different types of chemical analyses.
Using qualified methods, accreditation and proper documentation are all very important in manufacturing CRMs.
Using a certified reference material (CRM) can provide a high level of traceability and accuracy for measurements in the lab.
Internal standards can compensate for sample-prep and instrument variation, working with calibration curves to further improve data quality and validity.
Back-calculated accuracy, a measure of curve fitness, provides an easy method for determining results’ accuracy without performing additional runs.
Multi-point calibration of instruments is essential for consistency in cannabis laboratories, ensuring reproducible results.
The column will provide simple ways for laboratories to improve the quality of their chromatographic data, including instrument calibration and method development.